With the “High-Performance Computer and Quantum Simulator hybrid” (HPCQS) project, Europe is entering a new era of hybrid quantum high-performance computing. The aim is to closely connect two quantum simulators, each with over 100 qubits, with two European supercomputers. The infrastructure project is part of the research and innovation action “Advanced pilots towards the European exascale Supercomputers” and is funded by the European High-Performance Computing Joint Undertaking (EuroHPC JU) based in Luxembourg. HPCQS has a total budget of 12 million euros over 4 years, which is financed in equal parts by EuroHPC JU and the participating member states.