World events ranging from the Suez Canal blockage to the global COVID-19 pandemic have shown how susceptible our supply chain management and logistics systems are to changes in consumer and business demand, raw materials availability, shipping, and distribution. The field of constrained optimization is well matched to address these needs, yet today’s classical computers can hit a wall amidst growing volumes of data and unpredictable disruptions. New software solutions will combine the power of classical and quantum computing to help planners stay ahead.